منابع مشابه
On Approximating String Selection Problems with Outliers
Many problems in bioinformatics are about finding strings that approximately represent a collection of given strings. We look at more general problems where some input strings can be classified as outliers. The Close to Most Strings problem is, given a set S of same-length strings, and a parameter d, find a string x that maximizes the number of “non-outliers” within Hamming distance d of x. We ...
متن کاملA Three-String Approach to the Closest String Problem
Article history: Received 18 May 2010 Received in revised form 11 January 2011 Accepted 21 January 2011 Available online 28 January 2011
متن کاملIterative Rounding for the Closest String Problem
The closest string problem is an NP-hard problem, which arises in computational molecular biology and coding theory. Its task is to find a string that minimizes maximum Hamming distance to a given set of strings. This problem can be reduced to an integer program (IP). However, to date, there exists no known polynomial-time algorithm for integer programs. In 2004, Meneses et al. introduced a bra...
متن کاملA Closer Look at the Closest String and Closest Substring Problem
Let S be a set of k strings over an alphabet Σ; each string has a length between ` and n. The Closest Substring Problem (CSSP) is to find a minimal integer d (and a corresponding string t of length `) such that each string s ∈ S has a substring of length ` with Hamming distance at most d to t. We say t is the closest substring to S. For ` = n, this problem is known as the Closest String Problem...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2011
ISSN: 1471-2105
DOI: 10.1186/1471-2105-12-s1-s55